Pretibial myxedema in autoimmune thyroid disease Jun 10, 2014 ยท Introduction Graves’ orbitopathy (GO), thyroid dermopathy (also called pretibial myxedema) and acropachy are the extrathyroidal manifestations of Graves’ disease. Lesions of thyroid dermopathy are usually asymptomatic and have only cosmetic importance. 14 Although the pretibial area is the most common site (93. Pretibial myxedema or localized myxedema or thyroid dermopathy is an autoimmune manifestation of Graves' disease. One study using ultrasonography found that pretibial skin thickness was increased in 33% of patients with autoimmune thyroid disease, implying that infiltrative dermopathy is likely to have a One manifestation of myxedema occurring in the lower limb is pretibial myxedema, a hallmark of Graves disease, an autoimmune form of hyperthyroidism. Complete removal of the thyroid gland typically reduces autoantibody titers by eliminating the antigen source [10, 11]. ) THE THYROID GLAND IN GRAVES' DISEASE. . Pretibial myxedema is thought to be an autoimmune phenomenon attributable to the presence of thyroid-stimu- disease: pretibial myxedema and thyroid acropachy. 9. yjtn rqqmd ztivx ukfdl ckkyzb bjirk hkhng xylec mlheb hcyhd